Worst 2022 Mercedes-Benz E 350 Problems
Top 3 most-reported issues with average mileage at failure.
Electrical Faults
Forward Collision Avoidance: Adaptive Cruise Control
Forward Collision Avoidance: Warnings
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All Problems by Category
Every NHTSA complaint category for the 2022 Mercedes-Benz E 350.
| Component | Complaints | Crashes | Fires | Avg Mileage | Volume |
|---|---|---|---|---|---|
| Electrical Faults | 1 | — | — | — | |
| Forward Collision Avoidance: Adaptive Cruise Control | 1 | — | — | — | |
| Forward Collision Avoidance: Warnings | 1 | — | — | — | |
| Gasoline Fuel System | 1 | — | — | — | |
| Transmission / Drivetrain | 1 | — | — | — | |
| Unintended Acceleration | 1 | — | — | — |
Search Owner Complaints
Read what owners actually reported to NHTSA for the 2022 Mercedes-Benz E 350. Type a keyword (e.g. “transmission”, “stalling”, “brakes”) to filter.
Recalls for 2022 Mercedes-Benz E 350
3 NHTSA recall campaigns affecting ~231,623 vehicles.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
Other Mercedes-Benz E 350 Years
2022 Mercedes-Benz E 350 — FAQ
Answers based on real NHTSA complaint and recall data for this specific model year.
Is the 2022 Mercedes-Benz E 350 reliable?
What are common problems with the 2022 Mercedes-Benz E 350?
Does the 2022 Mercedes-Benz E 350 have any recalls?
Should I buy a 2022 Mercedes-Benz E 350?
Source: NHTSA (National Highway Traffic Safety Administration) complaint and recall databases, aggregated by VinItel.
Wider context: See the full Mercedes-Benz E 350 reliability report with year-by-year comparison and generation analysis.
Check Your Specific 2022 Mercedes-Benz E 350
Real owner complaints tell you about the model. The VIN tells you about your specific car — accidents, title issues, odometer fraud.
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